Using the unique pharmacokinetics of metals, developed risk
values for exposures to a series of metal compounds
including lead, mercury, cadmium, and zinc.
Critically examined and used the biokinetic model for
predicting blood levels and clean-up levels for lead in
various media for a variety of projects.
Working with industry sectors and a major trade
association, developed a strategic response to the Food
Quality and Protection Act (FQPA), particularly technical
issues such as aggregate exposures, cumulative risk via
common modes of action, and default safety factors to
distinguish between susceptibility of adult and perinatal
receptors. Strategic response included preparation of
white papers on specific technical issues, participation in
round-table discussions with representatives of registrants
and end-users of pesticides; rapporteur at public meetings;
meetings with Congressional staff; discussions with legal
counsel.
Prepared MSDS sheets for several small companies developing
novel chemicals for use in a variety of chemical
processes. The work also involved characterization of
both the chemical and toxicological properties of the
compound through design of standard tests.
Prepared and presented the first Margin-of-Exposure risk
characterization submitted to USEPA for dioxin-like
compounds.
Organized and managed a series of expert panels to provide
peer-review of USEPA's reassessment of the potential human
health hazards resulting from exposures to dioxin-like
chemicals. Tasks included panelist identification,
recruitment, preparation of draft comments to the Agency,
and preparation of manuscripts submitted to the
peer-reviewed literature based on the outcomes of panel
deliberations.
Reviewed, critically evaluated, and summarized data on the
toxic effects, background exposure levels, and risks
associated with exposure to a broad range of environmental
contaminants in environmental media. Much of this work
was done in the context of Superfund risk assessments or
state-specific regulations governing hazardous waste.
Reviewed water criteria documents for state and federal
jurisdictions for a paper and pulp manufacturer.
Chemicals considered included metals, chlorinated organics,
biological effluents.
Provided training to environmental managers within a large
petrochemical company covering all of the major USEPA
regulatory initiatives.
Performed risk assessments for consumer products containing
trace quantities of heavy metals and represented the
companies before CPSC.
